Small molecules which reverse FOXP3 Deficiency
Canned Analysis
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General Information
AccessionDCA00023072
TitleSmall molecules which reverse FOXP3 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by FOXP3 Deficiency in the Regulatory T cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21ef4e467bea600fbaee6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:3037
Cell TypeRegulatory T cells
Gene Symbol (human)FOXP3
Gene Symbol (mouse)Foxp3
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM870351, GSM870352
Perturbed SamplesGSM870355, GSM870356
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE35543
Gene Expression Omnibus
Natural and induced Foxp3+ regulatory T cells and Foxp3-deficient induced regulatory T cells
14
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