Small molecules which reverse PDCD10 KD
Canned Analysis
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General Information
AccessionDCA00023080
TitleSmall molecules which reverse PDCD10 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PDCD10 KD in the Primary endothelial cells passage 11 (senescent cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20c68e467bea600fba6f2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3041
Cell TypePrimary endothelial cells passage 11 (senescent cells)
Gene Symbol (human)PDCD10
Gene Symbol (mouse)Pdcd10
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1307897, GSM1307898, GSM1307899, GSM1307900, GSM1307901
Perturbed SamplesGSM1307906, GSM1307907, GSM1307908, GSM1307909, GSM1307910
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54095
Gene Expression Omnibus
Early and late passage endothelial cells with or without PDCD10 downregulation
14
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