Small molecules which reverse NCOA2 KO
Canned Analysis
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General Information
AccessionDCA00023090
TitleSmall molecules which reverse NCOA2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NCOA2 KO in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fd3ce467bea600fba040
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcarlfulp
CREEDS IDgene:46
Cell Typeheart
Gene Symbol (human)NCOA2
Gene Symbol (mouse)Ncoa2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1019090, GSM1019091, GSM1019092, GSM1019093
Perturbed SamplesGSM1019094, GSM1019095, GSM1019096, GSM1019097
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41558
Gene Expression Omnibus
Transcriptional regulator steroid receptor coactivator-2 deficiency effect on the heart
14
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