Small molecules which reverse GNMT KO
Canned Analysis
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General Information
AccessionDCA00023148
TitleSmall molecules which reverse GNMT KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GNMT KO in the Hepatocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2018ae467bea600fba228
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:3087
Cell TypeHepatocytes
Gene Symbol (human)GNMT
Gene Symbol (mouse)Gnmt
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM856045, GSM856046, GSM856047
Perturbed SamplesGSM856042, GSM856043, GSM856044
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE34838
Gene Expression Omnibus
Expression data from GNMT knockout mice in Hepatocytes and OKER cell lines
7
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