Small molecules which reverse SMARCA4 KO
Canned Analysis
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General Information
AccessionDCA00023162
TitleSmall molecules which reverse SMARCA4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SMARCA4 KO in the small intestine (jejunum) epithelium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20617e467bea600fba42a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3095
Cell Typesmall intestine (jejunum) epithelium
Gene Symbol (human)SMARCA4
Gene Symbol (mouse)Smarca4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1122267, GSM1122268, GSM1122274, GSM1122275
Perturbed SamplesGSM1122269, GSM1122270, GSM1122276, GSM1122277
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE46129
Gene Expression Omnibus
Transcriptome analysis of Brg1 deficient small intestinal epithelium in the context of normal and aberrant Wnt signalling
7
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