Small molecules which mimic TRIM28 KO in the B lineage
Canned Analysis
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General Information
AccessionDCA00023163
TitleSmall molecules which mimic TRIM28 KO in the B lineage
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TRIM28 KO in the B lineage in the Follicular B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22a30e467bea600fbb3d8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:3097
Cell TypeFollicular B cells
Gene Symbol (human)TRIM28
Gene Symbol (mouse)Trim28
Organismmouse
Perturbation Type KO in the B lineage
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM849309, GSM849310, GSM849311
Perturbed SamplesGSM849306, GSM849307, GSM849308
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34446
Gene Expression Omnibus
Gene expression analysis of wild type and KAP1 KO splenic B cells
14
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