Small molecules which reverse TRIM28 Conditional KO in the B lineage
Canned Analysis
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General Information
AccessionDCA00023166
TitleSmall molecules which reverse TRIM28 Conditional KO in the B lineage
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TRIM28 Conditional KO in the B lineage in the Transcriptional 2 Follicular Progenitor cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20661e467bea600fba44a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:3099
Cell TypeTranscriptional 2 Follicular Progenitor
Gene Symbol (human)TRIM28
Gene Symbol (mouse)Trim28
Organismmouse
Perturbation Type Conditional KO in the B lineage
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM849315, GSM849316, GSM849317
Perturbed SamplesGSM849312, GSM849313, GSM849314
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34446
Gene Expression Omnibus
Gene expression analysis of wild type and KAP1 KO splenic B cells
14
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