Small molecules which reverse PTRF KO
Canned Analysis
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General Information
AccessionDCA00023180
TitleSmall molecules which reverse PTRF KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PTRF KO in the lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e44e467bea600fbae9a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3105
Cell Typelung
Gene Symbol (human)PTRF
Gene Symbol (mouse)Ptrf
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1065357, GSM1065358, GSM1065359, GSM1065360, GSM1065361, GSM1065362
Perturbed SamplesGSM1065351, GSM1065352, GSM1065353, GSM1065354, GSM1065355, GSM1065356
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43561
Gene Expression Omnibus
Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking Cavin-1/PTRF
7
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