Small molecules which reverse PRDM14 KO
Canned Analysis
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General Information
AccessionDCA00023182
TitleSmall molecules which reverse PRDM14 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PRDM14 KO in the mESC mouse embryonic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e28e467bea600fbae8e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3106
Cell TypemESC mouse embryonic stem cells
Gene Symbol (human)PRDM14
Gene Symbol (mouse)Prdm14
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1105757, GSM1105758, GSM1105759
Perturbed SamplesGSM1105754, GSM1105755, GSM1105756
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45507
Gene Expression Omnibus
Genome-wide identification of genes differentially expressed between wild-type and Prdm14-deficient ES cells grown in 2i culture conditions.
7
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