Small molecules which reverse ING1 KO
Canned Analysis
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General Information
AccessionDCA00023184
TitleSmall molecules which reverse ING1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ING1 KO in the MEFs (Mouse embryonic fibroblasts) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21e32e467bea600fbae92
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3107
Cell TypeMEFs (Mouse embryonic fibroblasts)
Gene Symbol (human)ING1
Gene Symbol (mouse)Ing1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1060471, GSM1060472
Perturbed SamplesGSM1060475, GSM1060476
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43318
Gene Expression Omnibus
Gene expression changes in mouse embryonic fibroblasts (MEF cells) deficient for Ing1 and Gadd45a
14
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