Small molecules which reverse TNF Stimulation of gene product
Canned Analysis
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General Information
AccessionDCA00023198
TitleSmall molecules which reverse TNF Stimulation of gene product
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by TNF Stimulation of gene product in the Microvascular endothelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2179ae467bea600fbabde
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:3111
Cell TypeMicrovascular endothelial cells
Gene Symbol (human)TNF
Gene Symbol (mouse)Tnf
Organismhuman
Perturbation TypeStimulation of gene product
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM50771, GSM50772, GSM50773
Perturbed SamplesGSM50774, GSM50775, GSM50776
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2638
Gene Expression Omnibus
Tumor necrosis factor effect on microvascular endothelial cells
7
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