Small molecules which mimic ALDH1A2 KO
Canned Analysis
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General Information
AccessionDCA00023211
TitleSmall molecules which mimic ALDH1A2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ALDH1A2 KO in the posterior embryonic brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ac0e467bea600fba634
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:316
Cell Typeposterior embryonic brain
Gene Symbol (human)ALDH1A2
Gene Symbol (mouse)Aldh1a2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1065697, GSM1065698, GSM1065699, GSM1065700, GSM1065701
Perturbed SamplesGSM1065693, GSM1065694, GSM1065695, GSM1065696
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE43578
Gene Expression Omnibus
Retinoic acid deficiency effect on embryonic brain
21
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