Small molecules which mimic TET2 KO
Canned Analysis
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General Information
AccessionDCA00023215
TitleSmall molecules which mimic TET2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by TET2 KO in the hematopoietic stem cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d228c7e467bea600fbb338
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjoagap
CREEDS IDgene:3127
Cell Typehematopoietic stem cell
Gene Symbol (human)TET2
Gene Symbol (mouse)Tet2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM686818, GSM686819, GSM686822, GSM686823, GSM686826, GSM686827
Perturbed SamplesGSM686820, GSM686821, GSM686824, GSM686825, GSM686828, GSM686829, GSM686830, GSM686831
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27816
Gene Expression Omnibus
Effect of Tet2 loss in bone marrow progenitors
28
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