Small molecules which reverse APP Induced expression / Over-expression
Canned Analysis
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General Information
AccessionDCA00023226
TitleSmall molecules which reverse APP Induced expression / Over-expression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by APP Induced expression / Over-expression in the SHEP-SF neuroblastoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20aa7e467bea600fba62a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:315
Cell TypeSHEP-SF neuroblastoma
Gene Symbol (human)APP
Gene Symbol (mouse)App
Organismhuman
Perturbation TypeInduced expression / Over-expression
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM93710, GSM93712
Perturbed SamplesGSM93711, GSM93713
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4097
Gene Expression Omnibus
Amyloid precursor protein intracellular domain effect on neural cells
7
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