Small molecules which reverse SOCS3 KO
Canned Analysis
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General Information
AccessionDCA00023228
TitleSmall molecules which reverse SOCS3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SOCS3 KO in the multiple cell types cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f1eae467bea600fb9b90
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCadimo
CREEDS IDgene:32
Cell Typemultiple cell types
Gene Symbol (human)SOCS3
Gene Symbol (mouse)Socs3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM241738, GSM241740, GSM241742
Perturbed SamplesGSM241739, GSM241741, GSM241743
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE9549
Gene Expression Omnibus
Suppressor of cytokine signaling 3 deficiency effect on the regenerating liver
7
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