Small molecules which mimic LHX1 KO
Canned Analysis
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General Information
AccessionDCA00023231
TitleSmall molecules which mimic LHX1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LHX1 KO in the embryonic renal vesicles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d234c4e467bea600fbb882
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorantons
CREEDS IDgene:325
Cell Typeembryonic renal vesicles
Gene Symbol (human)LHX1
Gene Symbol (mouse)Lhx1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM174757, GSM174758, GSM174759, GSM174760, GSM174761
Perturbed SamplesGSM174762, GSM174763, GSM174764, GSM174891
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7257
Gene Expression Omnibus
Homeodomain protein Lim1 deficiency effect on embryonic renal vesicles
7
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