Small molecules which reverse PPARGC1A Deficiency
Canned Analysis
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General Information
AccessionDCA00023244
TitleSmall molecules which reverse PPARGC1A Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PPARGC1A Deficiency in the Aged gastrocnemius muscle - 24 months cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20103e467bea600fba1ec
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:338
Cell TypeAged gastrocnemius muscle - 24 months
Gene Symbol (human)PPARGC1A
Gene Symbol (mouse)Ppargc1a
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1269625, GSM1269626, GSM1269627
Perturbed SamplesGSM1269628, GSM1269629, GSM1269630
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52550
Gene Expression Omnibus
Peroxisome proliferator- coactivator-1 deficiency effect on aged gastrocnemius muscle
14
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