Small molecules which reverse EHMT2 KD
Canned Analysis
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General Information
AccessionDCA00023248
TitleSmall molecules which reverse EHMT2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EHMT2 KD in the MDA-MB231 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21ce3e467bea600fbae02
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:342
Cell TypeMDA-MB231
Gene Symbol (human)EHMT2
Gene Symbol (mouse)Ehmt2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM857535, GSM857536, GSM857537
Perturbed SamplesGSM857538, GSM857539, GSM857540
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34925
Gene Expression Omnibus
H3K9me2 methyltransferase G9a depletion effect on breast cancer cell line
12
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