Small molecules which reverse SOX2 Deficiency
Canned Analysis
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General Information
AccessionDCA00023252
TitleSmall molecules which reverse SOX2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SOX2 Deficiency in the AZ-521 gastric cancer (GC) cell line - 12 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d11e467bea600fbae16
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:347
Cell TypeAZ-521 gastric cancer (GC) cell line - 12 Hours
Gene Symbol (human)SOX2
Gene Symbol (mouse)Sox2
Organismhuman
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1053572, GSM1053573
Perturbed SamplesGSM1053582, GSM1053583
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE42937
Gene Expression Omnibus
Stem cell factor SOX2-deficient stomach carcinoma cell line: time course
28
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