Small molecules which mimic SOX2 Deficiency
Canned Analysis
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General Information
AccessionDCA00023255
TitleSmall molecules which mimic SOX2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SOX2 Deficiency in the AZ-521 gastric cancer (GC) cell line - 24 Hours cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21cbce467bea600fbadf0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:349
Cell TypeAZ-521 gastric cancer (GC) cell line - 24 Hours
Gene Symbol (human)SOX2
Gene Symbol (mouse)Sox2
Organismhuman
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1053577, GSM1053578, GSM1053579
Perturbed SamplesGSM1053587, GSM1053588, GSM1053589
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42937
Gene Expression Omnibus
Stem cell factor SOX2-deficient stomach carcinoma cell line: time course
28
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