Small molecules which reverse HMX1 Deficiency
Canned Analysis
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General Information
AccessionDCA00023258
TitleSmall molecules which reverse HMX1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HMX1 Deficiency in the Retinas of C57BL/6J cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d222c7e467bea600fbb092
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:351
Cell TypeRetinas of C57BL/6J
Gene Symbol (human)HMX1
Gene Symbol (mouse)Hmx1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1142797, GSM1142798, GSM1142799, GSM1142800
Perturbed SamplesGSM1142793, GSM1142794, GSM1142795, GSM1142796
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE47002
Gene Expression Omnibus
H6 family homoebox 1 deficiency effect on the retina
7
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