Small molecules which reverse CREBBP cpb heterozygous mice
Canned Analysis
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General Information
AccessionDCA00023268
TitleSmall molecules which reverse CREBBP cpb heterozygous mice
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CREBBP cpb heterozygous mice in the Hippocampus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d222a2e467bea600fbb082
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorevilla
CREEDS IDgene:355
Cell TypeHippocampus
Gene Symbol (human)CREBBP
Gene Symbol (mouse)Crebbp
Organismmouse
Perturbation Typecpb heterozygous mice
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM766001, GSM766002, GSM766003, GSM766004, GSM766005
Perturbed SamplesGSM766009, GSM766010, GSM766011, GSM766012, GSM766013
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE30880
Gene Expression Omnibus
Heterozygous null CREB binding protein mutant response to environmental enrichment: hippocampus
7
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