Small molecules which reverse GATA6 KO
Canned Analysis
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General Information
AccessionDCA00023272
TitleSmall molecules which reverse GATA6 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GATA6 KO in the Adult heart during pressure overload cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d222b4e467bea600fbb08a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:357
Cell TypeAdult heart during pressure overload
Gene Symbol (human)GATA6
Gene Symbol (mouse)Gata6
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1262797, GSM1262798
Perturbed SamplesGSM1262806, GSM1262807, GSM1262808
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE52317
Gene Expression Omnibus
Cardiomyocyte-specific Gata-4 or Gata-6 knockout effect on adult heart during pressure overload
14
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