Small molecules which reverse CBX2 KO
Canned Analysis
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General Information
AccessionDCA00023322
TitleSmall molecules which reverse CBX2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CBX2 KO in the E11.5 XX embryonic gonads cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d231c4e467bea600fbb72e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:380
Cell TypeE11.5 XX embryonic gonads
Gene Symbol (human)CBX2
Gene Symbol (mouse)Cbx2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM729418, GSM729419, GSM729420
Perturbed SamplesGSM729412, GSM729413, GSM729414
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29485
Gene Expression Omnibus
Polycomb group protein CBX2 deficiency effect on XY and XX embryonic gonads
14
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