Small molecules which reverse PDX1 KO
Canned Analysis
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General Information
AccessionDCA00023330
TitleSmall molecules which reverse PDX1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PDX1 KO in the Proximal small intestine cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d231a1e467bea600fbb71e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:387
Cell TypeProximal small intestine
Gene Symbol (human)PDX1
Gene Symbol (mouse)Pdx1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM719995, GSM719996, GSM719999, GSM720000
Perturbed SamplesGSM719994, GSM719997, GSM719998, GSM720001
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29048
Gene Expression Omnibus
Transcription factor pancreatic and duodenal homeobox 1 deficiency effect on proximal small intestine
7
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