Small molecules which mimic EZH2 Deficiency
Canned Analysis
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General Information
AccessionDCA00023333
TitleSmall molecules which mimic EZH2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by EZH2 Deficiency in the Hearts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d216b8e467bea600fbab78
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:391
Cell TypeHearts
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM744482, GSM744483, GSM744484, GSM744485, GSM744486
Perturbed SamplesGSM744487, GSM744488, GSM744489, GSM744490
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30076
Gene Expression Omnibus
Polycomb histone methyltransferase Ezh2-deficient hearts: right ventricle and interventricular septum
7
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