Small molecules which reverse MYCN OE
Canned Analysis
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General Information
AccessionDCA00023340
TitleSmall molecules which reverse MYCN OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYCN OE in the LUNG cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fd4fe467bea600fba048
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:40
Cell TypeLUNG
Gene Symbol (human)MYCN
Gene Symbol (mouse)Mycn
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM140827, GSM140863
Perturbed SamplesGSM140864, GSM140865
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6077
Gene Expression Omnibus
Proto-oncogene Nmyc overexpression effect on the embryonic lung
7
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