Small molecules which mimic KLF15 KO
Canned Analysis
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General Information
AccessionDCA00023379
TitleSmall molecules which mimic KLF15 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by KLF15 KO in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20147e467bea600fba20a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorzero323
CREEDS IDgene:446
Cell Typeheart
Gene Symbol (human)KLF15
Gene Symbol (mouse)Klf15
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1288174, GSM1288175, GSM1288176, GSM1288177
Perturbed SamplesGSM1288178, GSM1288179, GSM1288180
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53231
Gene Expression Omnibus
KLF14-deficient hearts during fasting
7
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