Small molecules which mimic SNCA KO
Canned Analysis
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General Information
AccessionDCA00023397
TitleSmall molecules which mimic SNCA KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SNCA KO in the Cerebellum - 6 month cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f42ce467bea600fb9c8a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:469
Cell TypeCerebellum - 6 month
Gene Symbol (human)SNCA
Gene Symbol (mouse)Snca
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM487046, GSM487047, GSM487048
Perturbed SamplesGSM487049, GSM487050, GSM487051
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19534
Gene Expression Omnibus
Alpha-synuclein deficiency effect on striatum and cerebellum: time course
45
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