Small molecules which reverse SNCA KO
Canned Analysis
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General Information
AccessionDCA00023404
TitleSmall molecules which reverse SNCA KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SNCA KO in the Striatum - 21 month cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23d15e467bea600fbbc2c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:472
Cell TypeStriatum - 21 month
Gene Symbol (human)SNCA
Gene Symbol (mouse)Snca
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM487066, GSM487067, GSM487068
Perturbed SamplesGSM487069, GSM487070, GSM487071
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19534
Gene Expression Omnibus
Alpha-synuclein deficiency effect on striatum and cerebellum: time course
45
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