Small molecules which reverse MIR222 KD
Canned Analysis
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General Information
AccessionDCA00023428
TitleSmall molecules which reverse MIR222 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MIR222 KD in the MCF7 breast cancer cells (fulvestrant-resistant) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2160fe467bea600fbab2e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:483
Cell TypeMCF7 breast cancer cells (fulvestrant-resistant)
Gene Symbol (human)MIR222
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM493918, GSM493919, GSM493920
Perturbed SamplesGSM493924, GSM493925, GSM493926
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19777
Gene Expression Omnibus
microRNA-221/222 knockdown effect on fulvestrant-resistant MCF7 breast cancer cells
14
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