Small molecules which mimic PRDM16 DEPLETION
Canned Analysis
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General Information
AccessionDCA00023431
TitleSmall molecules which mimic PRDM16 DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PRDM16 DEPLETION in the WAT - white adipose tissue (stromal-vascular cells) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21630e467bea600fbab3c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:487
Cell TypeWAT - white adipose tissue (stromal-vascular cells)
Gene Symbol (human)PRDM16
Gene Symbol (mouse)Prdm16
Organismmouse
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM860620, GSM860621
Perturbed SamplesGSM860624, GSM860625
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE35011
Gene Expression Omnibus
Rosiglitazone effect on PRDM16-deficient inguinal white adipose tissue: stromal-vascular cells
28
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