Small molecules which reverse SIRT4 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00023442
TitleSmall molecules which reverse SIRT4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SIRT4 KO in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22741e467bea600fbb28a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:49
Cell TypeLiver
Gene Symbol (human)SIRT4
Gene Symbol (mouse)Sirt4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1359081, GSM1359082, GSM1359083, GSM1359084, GSM1359085, GSM1359086
Perturbed SamplesGSM1359087, GSM1359088, GSM1359089, GSM1359090, GSM1359091, GSM1359092
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE56321
Gene Expression Omnibus
SIRT4 deficiency effect on the liver
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.