Small molecules which mimic EWSR1 KD
Canned Analysis
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General Information
AccessionDCA00023443
TitleSmall molecules which mimic EWSR1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by EWSR1 KD in the Ewing sarcoma and prostate cancer cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21d38e467bea600fbae24
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsolomoniyi
CREEDS IDgene:493
Cell TypeEwing sarcoma and prostate cancer
Gene Symbol (human)EWSR1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM679847, GSM679848, GSM679849
Perturbed SamplesGSM679854, GSM679855, GSM679856
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE27524
Gene Expression Omnibus
Transcription factor ETS fusion EWS/FLI1 knockdown in Ewing sarcoma cell line: time course
28
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