Small molecules which reverse GATA4 KO
Canned Analysis
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General Information
AccessionDCA00023466
TitleSmall molecules which reverse GATA4 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by GATA4 KO in the jejunum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f4ebe467bea600fb9cdc
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatordsurujon
CREEDS IDgene:510
Cell Typejejunum
Gene Symbol (human)GATA4
Gene Symbol (mouse)Gata4
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM281926, GSM281927, GSM281928
Perturbed SamplesGSM281929, GSM281930, GSM281931
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11194
Gene Expression Omnibus
Transcription factor GATA4 deficiency effect on the jejunum
7
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