Small molecules which mimic BRCA1 DEPLETION
Canned Analysis
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General Information
AccessionDCA00023479
TitleSmall molecules which mimic BRCA1 DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by BRCA1 DEPLETION in the Hela cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fa1ee467bea600fb9ee6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:529
Cell TypeHela cells
Gene Symbol (human)BRCA1
Gene Symbol (mouse)Brca1
Organismhuman
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM554070, GSM554072
Perturbed SamplesGSM554071, GSM554073
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22259
Gene Expression Omnibus
BRCA1 depletion effect on HeLa cells
14
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