Small molecules which mimic SFRP5 KO
Canned Analysis
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General Information
AccessionDCA00023491
TitleSmall molecules which mimic SFRP5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SFRP5 KO in the gonadal white adipose tissue HFD cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22b22e467bea600fbb444
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:54
Cell Typegonadal white adipose tissue HFD
Gene Symbol (human)SFRP5
Gene Symbol (mouse)Sfrp5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM921326, GSM921327, GSM921328, GSM921329, GSM921330, GSM921331, GSM921332
Perturbed SamplesGSM921333, GSM921334, GSM921335, GSM921336, GSM921337, GSM921338, GSM921339, GSM921340
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37514
Gene Expression Omnibus
Secreted frizzled-related protein 5 mutation effect on gonadal white adipose tissue
7
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