Small molecules which mimic EZH2 KO
Canned Analysis
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General Information
AccessionDCA00023495
TitleSmall molecules which mimic EZH2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by EZH2 KO in the Primary preadipocyte cultures cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20580e467bea600fba3e4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:542
Cell TypePrimary preadipocyte cultures
Gene Symbol (human)EZH2
Gene Symbol (mouse)Ezh2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM501365, GSM501366
Perturbed SamplesGSM501363, GSM501364
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE20054
Gene Expression Omnibus
Histone H3K27 methyltransferase Ezh2 deletion effect on primary preadipocyte cultures
7
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