Small molecules which reverse DICER1 Deficiency
Canned Analysis
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General Information
AccessionDCA00023500
TitleSmall molecules which reverse DICER1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DICER1 Deficiency in the Hepatocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2055ee467bea600fba3d6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:545
Cell TypeHepatocytes
Gene Symbol (human)DICER1
Gene Symbol (mouse)Dicer1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM300676, GSM300677, GSM300678, GSM300679, GSM300680
Perturbed SamplesGSM300681, GSM300682, GSM300683, GSM300684, GSM300685
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11899
Gene Expression Omnibus
Livers with Dicer1 deficient hepatocytes
7
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