Small molecules which mimic GATA4 INACTIVATION
Canned Analysis
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General Information
AccessionDCA00023501
TitleSmall molecules which mimic GATA4 INACTIVATION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA4 INACTIVATION in the Endothelial-derived cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20565e467bea600fba3d8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:546
Cell TypeEndothelial-derived cells
Gene Symbol (human)GATA4
Gene Symbol (mouse)Gata4
Organismmouse
Perturbation TypeINACTIVATION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM120064, GSM120065, GSM120066, GSM120067
Perturbed SamplesGSM120068, GSM120069, GSM120070, GSM120071
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5298
Gene Expression Omnibus
Zinc finger transcription factor Gata4 inactivation effect on endothelial-derived cells
7
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