Small molecules which reverse ADORA2B Deficiency
Canned Analysis
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General Information
AccessionDCA00023504
TitleSmall molecules which reverse ADORA2B Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ADORA2B Deficiency in the Heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20570e467bea600fba3de
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:547
Cell TypeHeart
Gene Symbol (human)ADORA2B
Gene Symbol (mouse)Adora2b
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM496724, GSM496725, GSM496726
Perturbed SamplesGSM496718, GSM496719, GSM496720
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE19875
Gene Expression Omnibus
A2B adenosine receptor deficient heart response to ischemic preconditioning and subsequent reperfusion
7
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