Small molecules which mimic SPARC Deficiency
Canned Analysis
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General Information
AccessionDCA00023513
TitleSmall molecules which mimic SPARC Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by SPARC Deficiency in the Lens epithelium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20a2ce467bea600fba5f4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:551
Cell TypeLens epithelium
Gene Symbol (human)SPARC
Gene Symbol (mouse)Sparc
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM338339, GSM338341, GSM338342
Perturbed SamplesGSM338336, GSM338338, GSM338340, GSM338343
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13402
Gene Expression Omnibus
Matricellular glycoprotein SPARC deficiency effect on lens epithelium
7
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