Small molecules which reverse EGR1 KO
Canned Analysis
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General Information
AccessionDCA00023516
TitleSmall molecules which reverse EGR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EGR1 KO in the Retina - 30 Days (POST-NATAL) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20a26e467bea600fba5f2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:552
Cell TypeRetina - 30 Days (POST-NATAL)
Gene Symbol (human)EGR1
Gene Symbol (mouse)Egr1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM424879, GSM424880, GSM424881, GSM424882
Perturbed SamplesGSM424883, GSM424884, GSM424885, GSM424886
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16974
Gene Expression Omnibus
Egr-1 deficiency effect on retina during eye development
14
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