Small molecules which reverse HDAC3 KO
Canned Analysis
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General Information
AccessionDCA00023520
TitleSmall molecules which reverse HDAC3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HDAC3 KO in the heart - 6 week old cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22158e467bea600fbaff2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:56
Cell Typeheart - 6 week old
Gene Symbol (human)HDAC3
Gene Symbol (mouse)Hdac3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM774636, GSM774637, GSM774638, GSM774639
Perturbed SamplesGSM774640, GSM774646, GSM774647, GSM774649
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE31251
Gene Expression Omnibus
Histone deacetylase 3 deficiency effect on the heart
7
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