Small molecules which reverse MAPK14 KO
Canned Analysis
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General Information
AccessionDCA00023524
TitleSmall molecules which reverse MAPK14 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MAPK14 KO in the liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21151e467bea600fba91e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorwokeefe
CREEDS IDgene:562
Cell Typeliver
Gene Symbol (human)MAPK14
Gene Symbol (mouse)Mapk14
Organismmouse
Perturbation TypeKO
None{u'vals': [0.260215976914, -0.255469138514, 0.146493900584, 0.115710084027, 0.0786018473641, 0.0777732104836, 0.070319248379, 0.0678291923003, 0.0585714082621, -0.0574922807271, -0.0507853097901, -0.0507335216157, 0.0502783213384, -0.0502143361832, -0.048
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM177040, GSM177041, GSM177042
Perturbed SamplesGSM177037, GSM177038, GSM177039
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE7342
Gene Expression Omnibus
p38alpha deficiency effect on the fetal liver
14
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