Small molecules which reverse IGF1 OE
Canned Analysis
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General Information
AccessionDCA00023530
TitleSmall molecules which reverse IGF1 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by IGF1 OE in the MCF-7 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21148e467bea600fba91a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorwokeefe
CREEDS IDgene:569
Cell TypeMCF-7
Gene Symbol (human)IGF1
Gene Symbol (mouse)Igf1
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM183423, GSM183424, GSM183425
Perturbed SamplesGSM183429, GSM183430, GSM183431
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE7561
Gene Expression Omnibus
Insulin-like growth factor-I effect on breast cancer cell line: time course
21
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