Small molecules which reverse KLF5 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00023538
TitleSmall molecules which reverse KLF5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by KLF5 KO in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21db9e467bea600fbae5e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:580
Cell TypeES cells
Gene Symbol (human)KLF5
Gene Symbol (mouse)Klf5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM234772, GSM234773
Perturbed SamplesGSM234774, GSM234775
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9244
Gene Expression Omnibus
Transcription factor Klf5 deficiency effect on embryonic stem cells
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.