Small molecules which reverse AQP11 Deficiency
Canned Analysis
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General Information
AccessionDCA00023570
TitleSmall molecules which reverse AQP11 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by AQP11 Deficiency in the Kidney cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22d39e467bea600fbb532
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:605
Cell TypeKidney
Gene Symbol (human)AQP11
Gene Symbol (mouse)Aqp11
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM267980, GSM267982, GSM267983, GSM267986, GSM267990, GSM267991, GSM267994
Perturbed SamplesGSM267981, GSM267984, GSM267985, GSM267987, GSM267988, GSM267989, GSM267992, GSM267993, GSM267995
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE10634
Gene Expression Omnibus
Aquaporin-11 deficiency effect on the kidney
7
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