Small molecules which reverse RB1 KD
Canned Analysis
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General Information
AccessionDCA00023578
TitleSmall molecules which reverse RB1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RB1 KD in the OSTEOBLASTS cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22839e467bea600fbb2fa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCopernicia
CREEDS IDgene:619
Cell TypeOSTEOBLASTS
Gene Symbol (human)RB1
Gene Symbol (mouse)Rb1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1220797, GSM1220803
Perturbed SamplesGSM1220821, GSM1220827
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50532
Gene Expression Omnibus
RB1-depleted osteoblast response to ionizing radiation: time course
77
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