Small molecules which mimic RB1 KD
Canned Analysis
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General Information
AccessionDCA00023581
TitleSmall molecules which mimic RB1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by RB1 KD in the OSTEOBLASTS cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23cc9e467bea600fbbc0a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCopernicia
CREEDS IDgene:650
Cell TypeOSTEOBLASTS
Gene Symbol (human)RB1
Gene Symbol (mouse)Rb1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1220792, GSM1220798
Perturbed SamplesGSM1220804, GSM1220810
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE50532
Gene Expression Omnibus
RB1-depleted osteoblast response to ionizing radiation: time course
77
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